Hunter New England Human Research Ethics Committee

Approval number: 2020/ETH00725

Australian New Zealand Clinical Trials Registry Number: ACTRN12620000527965

Newborn infants are potentially at increased risk from SARS-CoV-2 infection. In the midst of an unfolding global pandemic, there is a dearth of information on how COVID-19  affects newborn infants.

It is also unclear if SARS-CoV-2 is vertically transmitted from mother to fetus antenatally via maternal viraemia and transplacental transfer.


This study will contribute to an emerging and global body of information about COVID-19 in the perinatal period, enabling timely reporting and appropriate health service planning to ensure optimal outcomes for neonates, mothers and families.



The aim of this project is to investigate the population health impacts of COVID -19 in mothers and their newborn infants cared for in tertiary and non-tertiary neonatal facilities.

This study seeks to address the following:


  1. Incidence of COVID-19 in pregnant women and their newborn infants

  2. Describe the outcomes for mothers and their newborn infants with COVID-19

  3. Identify incidence of SARS-CoV-2 infection in the neonatal period and describe clinical course and outcomes for newborn infants with COVID-19

  4. Collaborate with international COVID-19 registries to inform global variations and outcomes in care of newborn infants


NCoS Project Team

Prof Julee Oei; University of New South Wales

Dr Javeed Travadi; University of Newcastle

Dr Archana Koirala; University of Sydney

Prof Adrienne Gordon; University of Sydney

Dr Himanshu Popat; University of Sydney

Dr Robert Guaran; Executive Clinical Advisor, Neonatology, NSW Perinatal Services Network

Project Officer: Ms Melanie Lewis; Research Officer-Clinical Midwifery Specialist


Participating Sites

  • New South Wales

    • NCoS Lead PIs - Prof Ju-Lee Oei & Dr Javeed Travadi

  • Queensland

    • State PI - Prof Helen Liley​

  • South Australia

    • State PI - Dr Amy Keir​

  • Western Australia

    • State Leads - Prof Sanjay Patole & A Prof Shailender Mehta​

  • Australian Capital Territory

    • State PI - Dr Nadia Schmidt Sotomayor​

  • Northern Territory

    • State PI - Dr Dennis Bonney​

If you are interested in participating and would like to receive further information please contact us and we will get back to you as soon as possible.


Frequently asked questions (FAQs)

  • Where can I find the study protocol?

If you need more information please contact the NCoS project officer at Melanie.Lewis@health.nsw.gov.au. The study protocol can be found here - NCoS protocol.

  • Does the study include mothers who were positive during early pregnancy but are now negative closer to or at delivery?

Yes. We aim to capture data on newborn infants born to mothers who tested positive for SARS-CoV-2 at any time during their current pregnancy.

  • Are births from all hospitals included?

The study plans to collect information on infants born to SARS-CoV-2 positive mothers who may deliver at any location. We also aim to capture any infant admitted in the neonatal period (first 28 days of life) at any hospital including paediatric wards who tests positive for SARS-CoV-2 infection.

  • Can we use our own hospital data for local projects?

Absolutely - there are no restrictions on local hospitals to use their own data for other studies or QI projects.

  • How do you plan on integrating Australian data with others around the world?

Invitations to collaborate will be sent to other similar efforts around the world. Data will be pooled to maintain privacy. Authorship will be inclusive following ICMJE guidelines.


Thanks for submitting!